Alzheimer disease (AD) is the most common form of age-related dementia. The etiology of AD is considered to be multifactorial as only a negligible percentage of cases have a familial or genetic origin. Glycogen synthase kinase-3 (GSK-3) is regarded as a critical molecular link between the two histopathological hallmarks of the disease, namely senile plaques and neurofibrillary tangles. In this review, we summarize current data regarding the involvement of this kinase in several aspects of AD development and progression, as well as key observations highlighting GSK-3 as one of the most relevant targets for AD treatment
Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that plays a part in a number of phys...
Open access peer-reviewed chapter.MM acknowledges grant support from EU-FP7 (Neuro.GSK3, project # 2...
AbstractThere are two different types of Alzheimers’ disease, familiar Alzheimers’ disease (FAD) and...
Alzheimer disease (AD) is the most common form of age-related dementia. The etiology of AD is consid...
Glycogen synthase kinase 3 (GSK3) is a constitutively active, proline-directed serine/threonine kina...
Glycogen synthase kinase (GSK)-3 has been proposed as the link between the two histopathological hal...
Originally discovered because of its role in the regulation of glucose metabolism, Glycogen Synthase...
Alzheimer’s Disease (AD) is characterized by development of beta amyloid (Aβ) plaques and hyper-phos...
Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed serine/threonine kinase with a pletho...
There are two different types of Alzheimers’ disease, familiar Alzheimers’ disease (FAD) and Sporadi...
Alzheimer's disease (AD) is a disorder without a molecular marker in peripheral tissues or a disease...
Glycogen synthase kinase 3 (GSK3) has been implicated in neurological disorders; therefore, it is no...
Background: Glycogen synthase kinase 3 (GSK-3) is the evolutionary well-preserved multifunctional ub...
Glycogen synthase kinase (GSK)-3 has been proposed as the link between the two histopathological hal...
Background: Glycogen synthase kinase 3 (GSK-3) is the evolutionary well-preserved multifunctional ub...
Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that plays a part in a number of phys...
Open access peer-reviewed chapter.MM acknowledges grant support from EU-FP7 (Neuro.GSK3, project # 2...
AbstractThere are two different types of Alzheimers’ disease, familiar Alzheimers’ disease (FAD) and...
Alzheimer disease (AD) is the most common form of age-related dementia. The etiology of AD is consid...
Glycogen synthase kinase 3 (GSK3) is a constitutively active, proline-directed serine/threonine kina...
Glycogen synthase kinase (GSK)-3 has been proposed as the link between the two histopathological hal...
Originally discovered because of its role in the regulation of glucose metabolism, Glycogen Synthase...
Alzheimer’s Disease (AD) is characterized by development of beta amyloid (Aβ) plaques and hyper-phos...
Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed serine/threonine kinase with a pletho...
There are two different types of Alzheimers’ disease, familiar Alzheimers’ disease (FAD) and Sporadi...
Alzheimer's disease (AD) is a disorder without a molecular marker in peripheral tissues or a disease...
Glycogen synthase kinase 3 (GSK3) has been implicated in neurological disorders; therefore, it is no...
Background: Glycogen synthase kinase 3 (GSK-3) is the evolutionary well-preserved multifunctional ub...
Glycogen synthase kinase (GSK)-3 has been proposed as the link between the two histopathological hal...
Background: Glycogen synthase kinase 3 (GSK-3) is the evolutionary well-preserved multifunctional ub...
Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that plays a part in a number of phys...
Open access peer-reviewed chapter.MM acknowledges grant support from EU-FP7 (Neuro.GSK3, project # 2...
AbstractThere are two different types of Alzheimers’ disease, familiar Alzheimers’ disease (FAD) and...
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